Patients with TBI May Find a Solution If They Buy Marijuana Online

Patients with traumatic brain injury (TBI) increasingly buy marijuana online to provide relief from this devastating condition. TBI represents a critical health issue in the United States, with alarming statistics of approximately 214,110 TBI-related hospitalizations in 2020, while 2021 saw 69,473 TBI-related deaths.

Conventional treatments commonly fall short. Many are exploring marijuana as a natural addition. A recent study has revealed how this plant promises to tackle numerous issues related to the condition.

Key Takeaways:

• CBN analogs (CP1-CP4) demonstrated improved druglike properties and potent neuroprotective activity.
• Trauma patients who tested positive for THC had a lower risk of death after their intracranial injury.
• THC can provide neuroprotection when given prior to an injury.

Overview of Traumatic Brain Injury

Traumatic brain injury (TBI) is a condition caused by an external force affecting the brain. It can result from a forceful impact on the head or body or when an object penetrates the skull. The two main types are penetrating and non-penetrating.

• Penetrating: Occurs when an object breaches the skull and enters brain tissue.
• Non-penetrating: When an external force is strong enough to move the brain within the skull.

It can cause various damages to the brain, including:

• Diffuse axonal injury (DAI)
• Concussion
• Hematomas
• Contusions
• Skull fractures

Long-term consequences of the condition can include chronic traumatic encephalopathy (CTE) and post-traumatic dementia (PTD). The leading causes of it are falls, blunt trauma accidents, vehicle-related injuries, assaults/violence, and explosions/blasts.

Patients aged 65 and older are at the highest risk for TBI-related hospitalization and death, primarily due to falls. Men are generally at higher risk for serious TBI across all age groups.

The Promise of Cannabinol in Fighting Brain Disorders

Scientists at the Salk Institute explored the oxytocin/ferroptosis-regulated cell death pathway and its relevance to neurological disorders such as Alzheimer’s, Parkinson’s, and traumatic brain injury. The researchers employed a fragment-based drug discovery (FBDD) strategy to develop novel neurotherapeutics based on cannabinol (CBN), a potent inhibitor of oxytocin/ferroptosis.

They revealed that:

• Four new CBN analogs (CP1-CP4) demonstrated improved druglike properties.
• The analogs exhibited potent neuroprotective activity against oxytocin/ferroptosis by inhibiting lipid peroxidation and mitochondrial ROS.

These analogs showed strong neuroprotective activity in cell models by reducing harmful oxidation processes and improving mitochondrial function. One analog, CP1, was particularly effective in a fruit fly model of traumatic brain injury.

The study provides a foundation for designing new CBN-based drugs to treat neurological and metabolic disorders associated with mitochondrial dysfunction.

Other Studies

A 2020 study examined the impact of alcohol, cigarettes, and cannabis use on concussion recovery in 307 patients. Researchers found that:

• Pre-injury marijuana use: 24.4% used cannabis regularly before their concussion.
• Post-injury marijuana use: 14.0% used cannabis regularly during their recovery.
• No impact on recovery time: None of the substances (alcohol, cigarettes, cannabis) speed up the recovery process.
• Reduced symptom severity: In the final two weeks of the study, weed use was associated with lower symptom severity scores.
• Lower mortality in trauma patients: In a separate analysis of trauma patients, those who tested positive for THC upon hospital arrival had lower mortality rates after TBI.

A 2017 review analyzed pre-clinical research on TBI, focusing on cannabinoids’ therapeutic benefits and how manipulating the body’s endocannabinoid system could alleviate their effects.

Key findings from the review include:

• THC, when administered before the injury, can offer neuroprotection. Even very low doses of THC reduce cognitive impairments in mice following injury.
• While most THC gets out of the body within five days, very low concentrations can persist for extended periods.
• Other cannabinoids like CBD may also contribute to the observed neuroprotective effects in patients exposed to marijuana.

Order Marijuana Online to Protect Your Brain

If you are suffering from post-concussion or want to protect yourself, a little bit of weed can keep you safe. Marijuana comes in various forms, each offering different benefits. Choosing the appropriate form depends on personal preferences and treatment goals.

Type of Weed	Description	Pros	Cons
Flower	Dried buds of the plant	Smoked in pipes, joints, or vaporizers Fast effects	Shorter duration
Pre-Rolls	Made from ground ganja flower	Smoked directly	Expensive than flower
Concentrates	Potent extracts containing high levels of THC (80-90%).	Strong effects, a small amount is enough to get a high.	Expensive
Cartridges	Pre-filled vape cartridges containing weed oil.	Smoother inhalation, quick effects	Price, require maintenance
Edibles	Food products infused with ganja, such as gummies or baked goods.	Strong effects, long-lasting	Longer onset (30 minutes to 2 hours)
Tinctures	Alcohol-based ganja extracts, taken sublingually (under the tongue).	Easy dosage measurement	Unpleasant taste
Topicals	Creams, balms, and lotions infused with ganja for external use.	Local pain treatment	Local effects only

Accessing cannabis products online for managing symptoms offers several conveniences:

• Home Delivery: Patients can order from home, avoiding needing in-person visits to pharmacies or clinics.
• Product Variety: An online shop provides a wider range of popular products from various brands, including various strains and forms (edibles, oils, topicals).
• Discreet Purchasing: More privacy and discretion.
• Information Availability: Detailed product descriptions and user reviews on these platforms empower patients to make informed choices.
• Cost-Effectiveness: Many customers buy weed online because it’s more affordable.
• Ease of Reordering: Simplify the reordering process so patients can maintain consistent treatment.

Tips You Should Know Before Using Marijuana

• Before initiating treatment, consult with a healthcare professional experienced in medical cannabis. Discuss your specific symptoms, medical history, and any current medications.
• Familiarize yourself with the status of the substance in your region. Laws vary significantly; some areas may require a prescription, while others allow an over-the-counter purchase.
• Determining the right dosage is integral for effective treatment. Begin with a low dose, around 2.5 mg to 5 mg of THC or CBD, especially if you are new to weed. Slowly increase the dosage based on your response while monitoring for side effects.
• Keeping track of how the substance affects your symptoms is important for optimizing treatment. Maintain a journal documenting dosages, forms used, timing, and changes in symptoms such as pain levels, mood fluctuations, sleep quality, and cognitive function.
• If side effects such as dizziness or cognitive impairment occur, adjust your dosage or switch to weed products with higher CBD content and lower THC levels.
• Incorporating it into a broader rehabilitation strategy can improve recovery from the condition. Continue participating in recommended therapies such as physical therapy or cognitive rehabilitation while using the substance to manage symptoms effectively.

Buy Cannabis Online and Get Relief

While the use of marijuana for TBI is not yet widespread, and research is ongoing, preliminary findings suggest promising results. Cannabinoids may offer neuroprotection in the recovery process. These compounds interact with the endocannabinoid system to trigger a cascade of protective mechanisms, potentially facilitating a smoother recovery.

GetLoud Cannabis is your go-to online cannabis dispensary for the best cannabis products. With everything from high-quality products of flowers to tasty edibles, we deliver the good vibes right to your door so you can kick back and enjoy your favorites without a hitch.

Frequently Asked Questions

What is the best strain for TBI?

Consider the specific symptoms and individual responses to cannabinoids. High-CBD products have neuroprotective properties and lower risk of intoxication, while balanced strains may offer additional benefits depending on the patient’s needs.

Should I choose full-spectrum or isolate cannabinoid products?

Consider full-spectrum products such as flower, edibles, or concentrates. Most studies indicate that weed’s neuroprotective and anti-inflammatory benefits likely stem from the synergistic effects of multiple cannabinoids rather than a single compound.

Do terpenes contribute to the healing process of TBI?

Despite the limited direct research on terpenes and intracranial injury in animal models, researchers can gain insights into the mechanism of terpenes by studying their impact on other diseases with similar pathological features.

Some terpenes, such as alpha-pinene, beta-caryophyllene, limonene, linalool, myrcene, and nerolidol, can suppress inflammatory cells.